Course Description
It includes the principles of biopharmaceutics, clearance, volume of distribution, orders of kinetics, compartmental models, plasma protein binding; first-pass and second-pass metabolism; physicochemical and dosage form factors influencing bioavailability; assessment and measurement of key biopharmaceutical properties, bioequivalence, and biopharmaceutical classification scheme (BCS); influence of dosage regimens on the plasma concentration-time profile of a drug in the body and factors involved in steady-state plasma concentration of a drug. Practice/lab: Dissolution, bioavailability, bioequivalence and relevant calculations; may use semi-log graph paper or software for computation.
Course ID: PHCT 412
Credit hours | Theory | Practical | Laboratory | Lecture | Studio | Contact hours | Pre-requisite | 3 | 5 | 5 | - |
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